Which Shakespearean play features the characters of Iago, Othello, and Desdemona?

The play that features the characters Iago, Othello, and Desdemona is "Othello." This tragedy focuses on themes of jealousy, betrayal, and racism, with Iago serving as the antagonist who manipulates Othello, a Moorish general in the Venetian army, against his wife Desdemona. The relationship between these three characters is central to the plot, as Iago's deceit leads to tragic consequences driven by Othello's misplaced trust and tragic flaws.

In contrast, the other choices present different narratives that do not include these specific characters. "Hamlet" centers on the Prince of Denmark and his struggle with revenge and madness. "Macbeth" tells the story of ambition and the supernatural influencing the Scottish general. "King Lear" deals with themes of madness and familial relationships through the story of an aging king and his daughters. Thus, "Othello" is uniquely identified by its trio of characters and their intertwining fates, making it the correct answer.